5 mg Phenylephrine HCI
200 mg Guaifenesin

Formulated to relieve symptoms of upper respiratory tract disorders such as sinusitis, vasomotor rhinitis and hayfever, as well as for the temporary relief of coughs associated with respiratory tract infections, sinusitis, pharyngitis, bronchitis, and asthma.

• Can my patients who have high blood pressure or patients with an increased heart rate take Liquibid PD-R?

I have numerous doctors who give it to patients with high blood pressure because Phenylephrine is alpha-selectivity and lack of effect on beta-adrenocoeptors results in outstanding reduction in nasal congestion without the increase in heart rate and blood pressure associated with Pseudoephedrine.

• Does Liquibid PD-R cause rebound congestion?

Phenylephrine is unlikely to cause rebound congestion due to its direct action on alpha adrenoceptors as opposed to production of norepinephrine.

• Why is Liquibid PD-R immediate release instead of sustained?

Liquibid PD-R is immediate release because of the patent Mucinex has on Guaifenesin. Mucinex has a patent on any extended release Guaifenesin (over 400mg).