100 mg Diphenhydramine HCI
120 mg Pseudoephedrine HCl

Caution should be exercised in patients with stenosing peptic ulcer, pyloroduodenal obstruction, or bladder-neck obstruction, hypertension, diabetes mellitus, ischemic hear diseases, hyperthyroidism, increased intraocular pressure narrow angle glaucoma and prostatic hypertrophy. Patients sixty (60) years and older may demonstrate an increased response to this drug combination, both in therapeutic effect and in the incidence of adverse reactions and hence a lower dose may be more appropriate for these patients.

Antihistamines and/or decongestants may cause excitability particularly in children. At doses higher than the recommended dose, nervousness, dizziness or sleeplessness may occur.

Preparations containing pseudoephedrine should be used with caution in the presence of hypertension; coronary artery disease; any other cardiovascular disease; glaucoma; prostatic hypertrophy; hyperthyroidism; diabetes. Antihistamines have an atropine-like action and, therefore, should be used with caution in patients with a history of bronchial asthma, increased intraocular pressure, hyperthyroidism, cardiovascular disease and hypertension.

This product is contraindicated in patients with hypersensitivity to antihistamines or sympathomimetic amines, in nursing mothers, in infants and in patients receiving monoamine ocidase inhibitor (MAOI) therapy (see Drug Interactions section of the package insert) or in patients with narrow angle glaucoma, urinary retention, peptic ulcer and during an asthmatic attack. Sympathomimetic amines are contraindicated in patients with severe hypertension or severe coronary artery disease.